ORM2-Specific antibody

Cat.#: 107438

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Product Information

  • Product Name
    ORM2-Specific antibody
  • Documents
  • Description
    ORM2-Specific Mouse Monoclonal antibody. Positive IF detected in HepG2 cells. Positive WB detected in human plasma tissue, A549 cells. Observed molecular weight by Western-blot: 45 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    AGP B' antibody; AGP2 antibody; Alpha 1 acid glycoprotein 2 antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of ORM2-Specific recombinant protein (Accession Number: NM_000608). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IF: 1:50-1:500

  • Validations

    human plasma tissue were subjected to SDS PAGE followed by western blot with Catalog No:107438(ORM2 Antibody) at dilution of 1:1000

    human plasma tissue were subjected to SDS PAGE followed by western blot with Catalog No:107438(ORM2 Antibody) at dilution of 1:1000

    Immunofluorescent analysis of (-20oc Ethanol) fixed HepG2 cells using Catalog No:107438(ORM2 Antibody) at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed HepG2 cells using Catalog No:107438(ORM2 Antibody) at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)

  • Background
    ORM2, also named as AGP2 and OMD 2, belongs to the calycin superfamily and Lipocalin family. It functions as transport protein in the blood stream. ORM2 binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability. ORM2 appears to function in modulating the activity of the immune system during the acute-phase reaction. ORM2 is one of the conserved endoplasmic reticulum membrane proteins which regulating lipid homeostasis and protein quality control. This antibody can specially recognize ORM2. It recognizes a band about 45 kDa in human plasma which may be due to the glycosylation of ORM2 or the dimer formation of the protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"