Cart 2

Oligophrenin 1 antibody

Cat.#: 113344

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Oligophrenin 1 antibody
  • Documents
  • Description
    Oligophrenin 1 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 92 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    MRX60 antibody; oligophrenin 1 antibody; OPHN1 antibody; OPN1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Oligophrenin 1 recombinant protein (Accession Number: BC059393). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113344(OPHN1 antibody) at dilution of 1:800

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113344(OPHN1 antibody) at dilution of 1:800

    IP Result of anti-OPHN1 (IP:Catalog No:113344, 3ug; Detection:Catalog No:113344 1:200) with mouse brain tissue lysate 8000ug.

    IP Result of anti-OPHN1 (IP:Catalog No:113344, 3ug; Detection:Catalog No:113344 1:200) with mouse brain tissue lysate 8000ug.

  • Background
    The OPHN1 gene encodes a Rho-GTPase activating protein (RhoGAP), and mutations in OPHN1 are responsible for non-specific X-linked mental retardation (NSMR). OPHN1 is highly expressed in the brain and present both pre- and postsynaptically in neurons.
  • References
    • Kim JH, Lee YC, Kim H. Additive lymph node dissection may be necessary in minute submucosal cancer of the stomach after endoscopic resection. Annals of surgical oncology. 19(3):779-85. 2012.
    • Sel S, Kaiser M, Nass N. Oligophrenin-1 (Ophn1) is expressed in mouse retinal vessels. Gene expression patterns : GEP. 12(1-2):63-7. 2012.
    • Barresi S, Tomaselli S, Athanasiadis A. Oligophrenin-1 (OPHN1), a gene involved in X-linked intellectual disability, undergoes RNA editing and alternative splicing during human brain development. PloS one. 9(3):e91351. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"