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Product Name
Oligophrenin 1 antibody
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Description
Oligophrenin 1 Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue, human stomach cancer tissue. Positive WB detected in mouse brain tissue, mouse skeletal muscle tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 91 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
MRX60 antibody; oligophrenin 1 antibody; OPHN1 antibody; OPN1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Oligophrenin 1 recombinant protein (Accession Number: BC059393). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113343(OPHN1 antibody) at dilution of 1:500
IP Result of anti-OPHN1 (IP:Catalog No:113343, 4ug; Detection:Catalog No:113343 1:500) with mouse brain tissue lysate 5200ug.
Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:113343(OPHN1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:113343(OPHN1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
The OPHN1 gene encodes a Rho-GTPase activating protein (RhoGAP), and mutations in OPHN1 are responsible for non-specific X-linked mental retardation (NSMR). OPHN1 is highly expressed in the brain and present both pre- and postsynaptically in neurons.
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