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Product Name
Human OMGP (aa 1-416, His Tag) recombinant protein
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Description
Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
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Protein name
Oligodendrocyte-myelin glycoprotein
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Protein short names
OMGP; OMG
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Uniprot ID
P23515
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Gene Name
OMG; OMGP
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human OMGP (P23515-1) (Met 1-Pro 416) without the pro peptide was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human OMGP comprises 403 amino acids and has a predicted molecular mass of 46 kDa. The apparent molecular mass of rh OMGP is approximately 120-130 kDa in SDS-PAGE under reducing conditions due to high glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. Human OMG immobilized at 0.8 μg/ml, 100 μl/well will mediate >15% C6 cell adhesion.
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Validations
Human OMGP / OMG Protein (aa 1-416, His Tag) SDS-PAGE
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