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Product Name
OASL Polyclonal Antibody
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Description
Polyclonal antibody to OASL
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Tested applications
WB
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Species reactivity
Human
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Alternative names
OASL antibody; OASLd antibody; TRIP-14 antibody; TRIP14 antibody; p59 OASL antibody; p59-OASL antibody; p59OASL antibody; 2'-5'-oligoadenylate synthetase like antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 315-514 of human OASL (NP_003724.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:1000
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Validations
Western blot - OASL Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using OASL antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 60s.
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Background
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"