NUP98-NUP96 antibody

NUP98-NUP96 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NUP98-NUP96 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells, HeLa cells, Jurkat cells, K-562 cells, MCF7 cells. Positive IP detected in COLO 320 cells. Observed molecular weight by Western-blot: 98kd

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

96 kDa nucleoporin antibody; ADAR2 antibody; ADIR2 antibody; Nucleoporin Nup96 antibody; NUP196 antibody; NUP96 antibody; NUP98 NUP96 antibody; NUP98-NUP96 antibody

Rabbit IgG

This antibody was obtained by immunization of NUP98-NUP96 recombinant protein (Accession Number: BC012906). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Nup98-Nup96 (also known as Nup196, ADIR2 or ADAR2), encoded by NUP98 gene, is a component of the nuclear pore complex (NPC) . It is first synthesized as 186-198 kDa Nup98-Nup96 precursors and the precursors shortly undergo autoproteolysis to give rise to two nucleoporins, the amino-terminal Nup98 (Nup98-N) and carboxy-terminal Nup96 (Nup96-C). Both of Nup98 and Nup96 are localized to the nucleoplasmic side of the NPC. This antibody was raised against the carboxy-terminal region of Nup98-Nup96, it recognizes all Nup98-Nup96 proteins except Nup98-N. Since the autoproteolysis is very rapid this antibody usually detected 98-115 kDa Nup96 protein in multiple cell lines. It is notable that RNA-editing deaminase 1 (Gene ID: 104), also named ADAR2, is a different protein from Nup98-Nup96 (ADAR2).