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Product Name
NUMBL antibody
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Description
NUMBL Mouse Monoclonal antibody. Positive IF detected in L02 cells. Positive IHC detected in human gliomas tissue. Positive WB detected in L02 cells. Observed molecular weight by Western-blot: 70 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human; other species not tested.
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Alternative names
CAG3A antibody; CTG3a antibody; NBL antibody; numb homolog (Drosophila) like antibody; Numb like protein antibody; NUMB R antibody; Numb related protein antibody; NUMBL antibody; NUMBLIKE antibody; NUMBR antibody; TNRC23 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of NUMBL recombinant protein (Accession Number: BC001794). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:107343(NUMBLIKE Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using Catalog No:107343(NUMBLIKE Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using Catalog No:107343(NUMBLIKE Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of L02 cells using Catalog No:107343(NUMBLIKE Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)
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Background
Numbl (also known as numblike or Nbl), as a conserved homolog of Drosophila Numb, is specfically expressed in the brain. Numbl is a cytoplasm protein and has redundant functions in embryonic neurogenesis. It plays an important role in ependymal wall integrity and subventricular zone neuroblast survival. However, its expression and function in the central nervous system lesion are still unclear.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"