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Product Name
Human C1D (GST Tag) recombinant protein
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Description
Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity).
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Protein name
Nuclear nucleic acid-binding protein C1D
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Protein short names
MGC12261; SUNCOR; NUCLEAR DNA BINDING PROTEIN; MGC14659; NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D; C1D DNA-BINDING PROTEIN; AI875855; SMALL UNIQUE NUCLEARRECEPTOR CO-REPRESSOR; LRP1; HC1D; SMALL UNIQUE NUCLEARRECEPTORCOREPRESSOR; C1DNUCLEARRECEPTOR CO-REPRESSOR; SMALL UNIQUE NUCLEAR CO-REPRESSOR; NUCLEAR DNA-BINDING PROTEIN; RRP47; 1110036E10RIK; SUN-COR; MC1D
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Uniprot ID
Q13901
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Gene Name
C1D
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human C1D (Q13901) (Met 1-Ser 141) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human C1D/GST chimera consists of 375 amino acids and has a predicted molecular mass of 43.2 kDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 80 % as determined by SDS-PAGE
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Validations
Human C1D Protein (GST Tag) SDS-PAGE
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