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Product Name
NOP58 antibody
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Description
NOP58 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 60kd
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
HSPC120 antibody; NOL5 antibody; NOP5 antibody; NOP5/NOP58 antibody; NOP58 antibody; Nucleolar protein 5 antibody; Nucleolar protein 58 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NOP58 recombinant protein (Accession Number: NM_015934). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:113305(NOP58 antibody) at dilution of 1:1000
IP Result of anti-NOP58 (IP:Catalog No:113305, 4ug; Detection:Catalog No:113305 1:500) with K-562 cells lysate 3600ug.
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Background
The box C/D snoRNPs,is named for the short, conserved box C (UGAUGA) and box D (CUGA) sequences present in their RNA moiety. The box C/D sequences are also required for multiple aspects. of snoRNA biogenesis, including: RNA stability, intronic processing, nucleolar targeting, nuclear retention, and 59 trimethylguanosine cap formation [PMID:9649444,8878486]. Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins [PMID:10606270].
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References
- Fong YW, Ho JJ, Inouye C, Tjian R. The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells. eLife. 3:. 2014.
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