NOP56 antibody

NOP56 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NOP56 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, A549 cells. Observed molecular weight by Western-blot: 58-66kd

ELISA, WB

human, mouse, rat; other species not tested.

NOP56 antibody; Nucleolar protein 56 antibody; Nucleolar protein 5A antibody; NOL5A antibody

Rabbit IgG

This antibody was obtained by immunization of NOP56 recombinant protein (Accession Number: NM_006392). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Box C/D RNA-protein complexes (RNPs) guide the 2'-O-methylation of nucleotides in eukaryotic ribosomal RNAs. The box C/D and C'/D' RNP subcomplexes are each assembled with three sRNP core proteins. The Nop56 core protein mediates crucial protein-protein interactions required for both sRNP assembly and the methyltransferase reaction by bridging the L7Ae and fibrillarin core proteins [PMID:22496443]. NOP56 is a component of the box C/D small nucleolar ribonucleoprotein complexes that direct 2-prime-O-methylation of pre-ribosomal RNA (rRNA) during its maturation. It is predicted to function in an early to middle step in pre-rRNA processing [PMID:12777385].