-
Product Name
nNOS antibody
- Documents
-
Description
nNOS Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue.
-
Tested applications
ELISA, IHC
-
Species reactivity
Human; other species not tested.
-
Alternative names
bNOS antibody; Constitutive NOS antibody; IHPS1 antibody; N NOS antibody; NC NOS antibody; Neuronal NOS antibody; Nitric oxide synthase antibody; brain antibody; nNOS antibody; NOS antibody; NOS type I antibody; NOS1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000620). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
IHC: 1:20-1:200
-
Validations
Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human kidney using Catalog No:113259(nNOS antibody) at dilution of 1:100 (under 40x lens)
-
Background
nNOS belongs to the NOS family. NOS1 produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1).The antibody can recognize isoform 1,2,4 of NOS1.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"