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Product Name
NMU Polyclonal Antibody
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Description
Polyclonal antibody to NMU
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Tested applications
IHC
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Species reactivity
Human, Mouse
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Alternative names
NMU antibody; neuromedin-U antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 35-174 of human NMU (NP_006672.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:100
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Validations
Immunohistochemistry - NMU Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver using NMU antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - NMU Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human esophagus using NMU antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - NMU Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human stomach using NMU antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - NMU Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse lung using NMU antibody at dilution of 1:100 (40x lens).
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Background
Neuromedin-U-25: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.; Neuromedin precursor-related peptide 33: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36.; Neuromedin precursor-related peptide 36: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
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