NKRF antibody

NKRF antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NKRF Rabbit Polyclonal antibody. Positive IP detected in A549 cells. Positive WB detected in Jurkat cells, A431 cells, A549 cells, HepG2 cells, PC-3 cells. Observed molecular weight by Western-blot: 100 kDa

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

ITBA4 antibody; NF kappa B repressing factor antibody; NKRF antibody; NRF antibody; Protein ITBA4 antibody; Transcription factor NRF antibody

Rabbit IgG

This antibody was obtained by immunization of NKRF recombinant protein (Accession Number: NM_001173488). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

NKRF, also named as Protein ITBA4 or Transcription factor NRF, is a 690 amino acid protein, which contains one G-patch domain and one R3H domain. NKRF is Widely and constitutively expressed, with lower level in colon, peripheral blood lymphocytes, lung and kidney. NKRF interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. NKRF is involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity.

• Huang L, Liu Y, Wang L. Down-regulation of miR-301a suppresses pro-inflammatory cytokines in Toll-like receptor-triggered macrophages. Immunology. 140(3):314-22. 2013.