NFKB2 antibody

NFKB2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NFKB2 Rabbit Polyclonal antibody. Positive WB detected in Apoptosised HeLa cells. Observed molecular weight by Western-blot: 100kd

ELISA, WB

Human, Mouse; other species not tested.

DNA binding factor KBF2 antibody; H2TF1 antibody; LYT 10 antibody; LYT10 antibody; NFKB2 antibody; p100 antibody; NFKB2 antibody; p52 antibody; p100 antibody; Oncogene Lyt 10 antibody; p100 antibody; p52 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_001261403). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. P52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. P52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65. This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human NFKB2.