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Product Name
Human MMP-8 / MMP8 recombinant protein
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Description
Can degrade fibrillar type I, II, and III collagens.
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Protein name
Neutrophil collagenase
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Protein short names
BB138268; HNC; CLG1; MMP8; MMP-8; PMNL-CL; NEUTROPHIL COLLAGENASE
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Uniprot ID
P22894
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Gene Name
MMP8; CLG1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the pro form of human MMP8 (NP_002415.1) (Phe 21-Gly 467) was expressed and purified, with an initial Met at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MMP8 consisting of 448 amino acids and has a calculated molecular mass of 52 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (AnaSpec, Catalog # 27076). The specific activity is > 400 pmoles/min/μg.
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Validations
Human MMP-8 / CLG1 Protein SDS-PAGE
Related Products / Services
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