NET1 Polyclonal Antibody

Cat.#: 160961

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Product Information

  • Product Name
    NET1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to NET1
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    NET1 antibody; ARHGEF8 antibody; NET1A antibody; neuroepithelial cell transforming 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NET1 (NP_001040625.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - NET1 Polyclonal Antibody

    Western blot - NET1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using NET1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 15s.

    Immunofluorescence - NET1 Polyclonal Antibody

    Immunofluorescence - NET1 Polyclonal Antibody

    Immunofluorescence analysis of HeLa cells using NET1 antibody . Blue: DAPI for nuclear staining.

  • Background
    Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"