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Product Name
Rat CD10/Neprilysin (His Tag) recombinant protein
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Description
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (By similarity). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2966343).
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Protein name
Neprilysin
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Protein short names
CALLA; C85356; DKFZP686O16152; MGC126707; NEP; 6030454K05RIK; NEUTRAL ENDOPEPTIDASE; CD10; MME; MGC126681; SFE; NEPRILYSIN
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Uniprot ID
P07861
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Gene Name
Mme
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat MME (P07861) (Tyr52-Trp750) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat MME comprises 719 amino acids and has a predicted molecular mass of 82.5 kDa. The apparent molecular mass of the protein is approximately 93 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Rat CD10 / Neprilysin / MME Protein (His Tag) SDS-PAGE
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