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Product Name
NEK11 antibody
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Description
NEK11 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells. Observed molecular weight by Western-blot: 54kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ23495 antibody; NEK11 antibody; NimA related protein kinase 11 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NEK11 recombinant protein (Accession Number: NM_001321223). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:113101(NEK11 antibody) at dilution of 1:400
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Background
NEK11(Serine/threonine-protein kinase) belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses.It controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.It has 4 isoforms produced by alternative splicing.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"