NCOA7 antibody

Cat.#: 113045

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Product Information

  • Product Name
    NCOA7 antibody
  • Documents
  • Description
    NCOA7 Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells, MCF7 cells. Observed molecular weight by Western-blot: 120-130 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    dJ187J11.3 antibody; ERAP140 antibody; ESNA1 antibody; FLJ45605 antibody; Nbla00052 antibody; Nbla10993 antibody; NCOA7 antibody; nuclear receptor coactivator 7 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of NCOA7 recombinant protein (Accession Number: XM_024446331). Purification method: Antigen Affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:113045(NCOA7 Antibody) at dilution of 1:1000

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:113045(NCOA7 Antibody) at dilution of 1:1000

    IP Result of anti-NCOA7 (IP:Catalog No:113045, 4ug; Detection:Catalog No:113045 1:1000) with HEK-293 cells lysate 3600ug.

    IP Result of anti-NCOA7 (IP:Catalog No:113045, 4ug; Detection:Catalog No:113045 1:1000) with HEK-293 cells lysate 3600ug.

  • Background
    Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. NCoA-7 (nuclear receptor coactivator 7), also known as ESNA1 or ERAP140, is a 942 amino acid nuclear protein that enhances nuclear eceptor transcriptional activities and coactivates several nuclear receptors including PPARG, ESR1, THRB and RARA. Highly expressed in brain and weakly expressed in pancreas, bladder, ovary, spinal cord, prostate, mammary gland, ovary, uterus and stomach, NCoA-7 is a member of the OXR1 family and contains one LysM repeat and a TLD domain. Six NCoA-7 isoforms are known to exist due to alternative splicing events, and the gene encoding NCoA-7 maps to human chromosome 6q22.31 and mouse chromosome 10 A4.This antibody is a rabbit polyclonal antibody raised against the C-terminal of human NCOA7 protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"