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Product Name
NAT8B Polyclonal Antibody
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Description
Polyclonal antibody to NAT8B
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Tested applications
IF
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Species reactivity
Human
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Alternative names
NAT8B antibody; CML2 antibody; Hcml2 antibody; NAT8BP antibody; putative N-acetyltransferase 8B antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 75-165 of human NAT8B (NP_057431.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IF 1:50 - 1:200
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Validations
Immunofluorescence - NAT8B Polyclonal Antibody
Immunofluorescence analysis of A549 cells using NAT8B antibody . Blue: DAPI for nuclear staining.
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Background
May have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1. May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"