Narsoplimab reference antibody

Cat.#: 177102

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Product Information

  • Product Name
    Narsoplimab reference antibody
  • Documents
  • Description
    Anti-MASP2 Antibody (Narsoplimab)
  • Tested applications
    ELISA
  • Species reactivity
    Human MASP2
  • Isotype
    IgG4
  • Preparation
    Recombinant expression and purified from CHO cells.
  • Clonality
    Monoclonal
  • Formulation
    0.1 M Pro-Ac, 20 mM Arg, pH 5.0
  • Storage instructions
    -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
  • Validations

    SDS-PAGE

    SDS-PAGE

    Anti-MASP2 Antibody (narsoplimab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

    SEC-HPLC

    SEC-HPLC

    The purity of Anti-MASP2 Antibody (narsoplimab) is 98.94%, determined by SEC-HPLC.

    Bioactivity: ELISA

    Bioactivity: ELISA

    Immobilized human MASP 2A His at 2 ug/mL can bind Anti-MASP2 Antibody (narsoplimab), EC50=0.006278 ug/mL.

    Function: Pathway

    Function: Pathway

    C5b-C9 of the MBL pathway can be completely inhibited by Anti-MASP2 Antibody (narsoplimab) with an IC50 of 0.7337 ug/mL.

    Function: Pathway

    Function: Pathway

    Narsoplimab block C4b production,IC50=0.91 ug/mL.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"