NARF antibody

NARF antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

NARF Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, human lung tissue, human placenta tissue, mouse testis tissue. Observed molecular weight by Western-blot: 52kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

DKFZp434G0420 antibody; FLJ10067 antibody; IOP2 antibody; NARF antibody

Rabbit IgG

This antibody was obtained by immunization of NARF recombinant protein (Accession Number: NM_001083608). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Prelamin A, is processed in the nucleus to lamin A by removal of its final 18 amino acids, including the cysteine residue in its C-terminal CAAX box, which is farnesylated. Nuclear prelamin A recognition factor (NARF) binds the farnesylated prelamin A C-terminal domain(preAct)(PMID:10514485). NARF, at 52 kDa, also named as IOP2, is a small enough protein to freely diffuse through the nuclear pore complex and may be retained within the nucleus by binding nuclear proteins and it has all of the information necessary to be imported into the nucleus(PMID:10514485). It has 3 isoforms produced by alternative splicing with the molecular mass of 51 kDa, 56 kDa and 46 kDa,respectively.