MYSM1 Polyclonal Antibody

Cat.#: 163756

Special Price 290.3 USD

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Product Information

  • Product Name
    MYSM1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to MYSM1
  • Tested applications
    WB, FC
  • Species reactivity
    Human, Mouse
  • Alternative names
    MYSM1 antibody; 2A-DUB antibody; 2ADUB antibody; histone H2A deubiquitinase MYSM1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human MYSM1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
    FC 1:20 - 1:50
  • Validations

    Western blot - MYSM1 Polyclonal Antibody

    Western blot - MYSM1 Polyclonal Antibody

    Western blot analysis of extracts of HeLa cells, using MYSM1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"