Myozenin 2 antibody

Myozenin 2 antibody

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Myozenin 2 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 30-35kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

C4orf5 antibody; Calsarcin-1 antibody; FATZ related protein 2 antibody; MYOZ2 antibody; Myozenin 2 antibody

Rabbit IgG

This antibody was obtained by immunization of Myozenin 2 recombinant protein (Accession Number: NM_016599). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

MYOZ2 gene encodes for the calcineurin-binding protein myozenin-2 (or Calsarcin-1) belonging to myozenin family. Defects in MYOZ2 gene are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder characterized by ventricular hypertrophy. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death (PMID: 17347475). Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, and gamma-filamin. Important role in the modulation of calcineurin signaling and myofibrillogenesis of myozenin-2 have been elucidated (PMID: 11114196). Proteintech’s Myozenin-2 antibody 11450-1-AP was raised against full-length protein of human origin and is able to detect band of approximate 34 kDa in Western blotting.