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Product Name
MYL7 antibody
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Description
MYL7 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, human heart tissue, mouse skeletal muscle tissue. Positive IP detected in mouse heart tissue. Positive IHC detected in human heart tissue. Observed molecular weight by Western-blot: 19 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
MLC 2a antibody; MLC2a antibody; MYL2A antibody; MYL7 antibody; MYLC2A antibody; Myosin light chain 2a antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MYL7 recombinant protein (Accession Number: NM_021223). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:112969(MYL7 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human heart using Catalog No:112969(MYL7 antibody) at dilution of 1:100 (under 10x lens)
IP Result of anti-MYL7 (IP:Catalog No:112969, 4ug; Detection:Catalog No:112969 1:700) with mouse heart tissue lysate 4000ug.
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Background
MYL7, also known as myosin light chain 2a (MLC2a), is essential for heart development. The expression of MYL7 in heart is predominatantly restricted to the atrium. So its expression has been considered as useful marker for atrial cardiomyocytes.
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References
- Zhao Y, Londono P, Cao Y. High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. Nature communications. 6:8243. 2015.
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