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Product Name
Mouse CD33 / Siglec-3 (Fc Tag) recombinant protein
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Description
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
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Protein name
Myeloid cell surface antigen CD33
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Protein short names
SIGLEC-3; SIGLEC3; CD33; P67; FLJ00391; GP67
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Uniprot ID
Q63994
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Gene Name
Cd33; Siglec3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of mouse CD33 (Q63994-1) (Met 1-Glu 240) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse CD33/Fc is a disulfide-linked homodimer. The reduced monomer comprises 465 amino acids and has a calculated molecular mass of 51.6 kDa. As a result of glycosylation, the apparent molecular mass of rm CD33/Fc monomer is approximately 55-60 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Mouse CD33 / Siglec-3 Protein (Fc Tag) SDS-PAGE
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