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Product Name
MYBPC3 antibody
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Description
MYBPC3 Rabbit Polyclonal antibody. Positive WB detected in human heart tissue. Observed molecular weight by Western-blot: 141kd,95-103kd
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Tested applications
ELISA, WB
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Species reactivity
human; other species not tested.
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Alternative names
MYBPC3 antibody; DKFZp779E1762 antibody; CMH4 antibody; FHC antibody; Cardiac MyBP C antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000256). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:112914(MYBPC3 antibody) at dilution of 1:500
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Background
MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4). The antibody recognizes the C-term of MYBPC3.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"