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Product Name
MXD1 antibody
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Description
MXD1 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells. Positive IP detected in HepG2 cells. Observed molecular weight by Western-blot: 25 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
MAD antibody; MAD1 antibody; MAX dimerization protein 1 antibody; Max dimerizer 1 antibody; MXD1 antibody; Protein MAD antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_002357). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112910(MXD1 antibody) at dilution of 1:500
IP Result of anti-MXD1 (IP:Catalog No:112910, 4ug; Detection:Catalog No:112910 1:500) with HepG2 cells lysate 3000ug.
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Background
MXD1, also named as MAD, is a transcriptional repressor. MAD1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"