Product Name

MUL1 antibody

Documents

Description

MUL1 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue. Positive WB detected in Transfected HEK-293 cells.

Tested applications

ELISA, IHC, WB, IF

Species reactivity

Human,Mouse,Rat; other species not tested.

Alternative names

C1orf166 antibody; FLJ12875 antibody; GIDE antibody; MAPL antibody; MUL1 antibody; MULAN antibody; RING finger protein 218 antibody; RNF218 antibody; RP11 401M16.2 antibody

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of MUL1 recombinant protein (Accession Number: NM_024544). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

WB: 1:500-1:5000

IHC: 1:20-1:200

IF: 1:10-1:100

Validations

Immunohistochemical of paraffin-embedded human kidney using Catalog No:112894(MUL1 antibody) at dilution of 1:50 (under 10x lens)

Immunohistochemical of paraffin-embedded human kidney using Catalog No:112894(MUL1 antibody) at dilution of 1:50 (under 40x lens)

Immunofluorescent analysis of HepG2 cells, using Catalog No:112894 and Rhodamine-labeled goat anti-rabbit IgG (red).

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:112894(MUL1 Antibody) at dilution of 1:1000

Background

Mitochondrial ubiquitin ligase 1 (MUL1),MAPL, MULAN, or gGIDE, was identified as an E3 protein ligase by three independent groups. Work in mammalian systems shows that MUL1 has small ubiquitin-like modifier (SUMO) ligase activity, stabilizing Drp1, or ubiquitin ligase activity, degrading Mfn. MUL1 expression in mammalian cells results in smaller and more fragmented mitochondria.

MUL1 antibody

Product Information

Related Products / Services