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Product Name
Human MUC-1/Mucin 1/CD227 (Fc Tag) recombinant protein
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Description
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
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Protein name
Mucin-1
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Protein short names
KL-6; PEMT; MUC1; MUCIN 1; MCD; PUM; MCKD1; PEM; MUC-1 MUCIN 1; RP11-263K19.2; EMA; ADMCKD; CA15-3; MUC1/ZD; CD227; H23AG; MCKD; MUC-1; ADMCKD1; MAM6; MUC-1/SEC; MUC-1/X
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Uniprot ID
P15941
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Gene Name
MUC1; PUM
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MUC1 isoform 2 (NP_001018016.1) extracellular domain (Met1-Gly167) was fused with the Fc region of mouse IgG at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MUC1/mFc is a disulfide-linked homodimer. The reduced monomer consists of 369 amino acids after removal the signal peptide and has a predicted molecular mass of 41 kDa. As a result of glycosylation, rhMUC1/mFc monomer migrates as an approximately 50.2 and 34.8 kDa band in SDS-PAGE under reducing conditions.
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Purity
( 84.9+9.2) % as determined by SDS-PAGE
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Validations
Human Mucin-1 / MUC-1 Protein (Fc Tag) SDS-PAGE
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