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Product Name
MRC1 Polyclonal Antibody
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Description
Polyclonal antibody to MRC1
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
MRC1 antibody; CD206 antibody; CLEC13D antibody; CLEC13DL antibody; MMR antibody; MRC1L1 antibody; bA541I19.1 antibody; hMR antibody; mannose receptor C-type 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 610-860 of human MRC1 (NP_002429.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - MRC1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using MRC1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5s.
Immunohistochemistry - MRC1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human lung using MRC1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - MRC1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse prostate using MRC1 antibody at dilution of 1:100 (40x lens).
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Background
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.; (Microbial infection) Interacts with Hepatitis B virus envelope protein.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"