MPI antibody

Cat.#: 112744

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Product Information

  • Product Name
    MPI antibody
  • Documents
  • Description
    MPI Rabbit Polyclonal antibody. Positive IF detected in NIH/3T3 cells. Positive IP detected in mouse brain tissue. Positive WB detected in human brain tissue, mouse brain tissue. Observed molecular weight by Western-blot: 43 kDa
  • Tested applications
    ELISA, WB, IP, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ39201 antibody; Mannose 6 phosphate isomerase antibody; mannose phosphate isomerase antibody; MPI antibody; Phosphohexomutase antibody; Phosphomannose isomerase antibody; PMI antibody; PMI1 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of MPI recombinant protein (Accession Number: NM_002435). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IF: 1:50-1:500

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:112744(MPI antibody) at dilution of 1:1200

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:112744(MPI antibody) at dilution of 1:1200

    IP Result of anti-MPI (IP:Catalog No:112744, 4ug; Detection:Catalog No:112744 1:1000) with mouse brain tissue lysate 4000ug.

    IP Result of anti-MPI (IP:Catalog No:112744, 4ug; Detection:Catalog No:112744 1:1000) with mouse brain tissue lysate 4000ug.

    Immunofluorescent analysis of (-20oc Ethanol) fixed NIH/3T3 cells using Catalog No:112744(MPI Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed NIH/3T3 cells using Catalog No:112744(MPI Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    MPI(mannose-6-phosphate isomerase) is also named as PMI1 and belongs to the mannose-6-phosphate isomerase type 1 family. It is a zinc metalloenzyme that catalyzes the reversible isomerization of mannose-6-phosphate and fructose-6-phosphate. MPI plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. This proterin has 2 isoforms produced by alternative splicing.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"