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Product Name
Mouse PLA2G2A recombinant protein (C-His)
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Description
Phospholipase A2, membrane associated, also known as Phosphatidylcholine 2-acylhydrolase 2A, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2 and PLA2G2A, is a peripheral membrane protein which belongs to the phospholipase A2 family. PLA2G2A is found in many cells and also extracellularly. The membrane-bound and secreted forms of PLA2G2A are identical. PLA2G2A has been proposed to play a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. PLA2G2A is thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. PLA2G2A catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2A might be a factor in human colorectal tumorigenesis.
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Protein name
Phospholipase A2, membrane associated
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Protein short names
EF,Mom1,Pla2,sPLA2,sPla2-IIA
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Uniprot ID
P31482
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Gene Name
Phospholipase A2, membrane associated; EC 3.1.1.4; Enhancing factor; EF; GIIC sPLA2; Group IIA phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse PLA2G2A (NP_001076000.1) (Asn22-Cys146) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse PLA2G2A consists of 135 amino acids and predicts a molecular mass of 15.3 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse PLA2G2A Protein 15467
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