-
Product Name
Mouse Pla2g1b/Pla2 (His tag) recombinant protein
- Documents
-
Description
Mouse phospholipase A2 is a secreted protein which belongs to the phospholipase A2 family. Phospholipase A2/PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. PLA2G1B has been thought to play major role in digestion of glycerophospholipids in nutrients, given its abundance in digestive organs. Since its expression has been observed in non-digestive organs including the lung, spleen, kidney, ovary, retina, brain, and neurons, its function may not limited to digestive role. PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
-
Protein name
phospholipase A2, group IB, pancreas(Pla2g1b)
-
Protein short names
Pla2
-
Uniprot ID
Q9Z0Y2
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Pla2g1b/Pla2 Ala16-Cys146 is expressed with a 6His tag at the C-terminus.
-
Protein Species
Mouse
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Mouse Pla2g1b/Pla2 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"