Mouse CD1d (His & Fc Tag) recombinant protein

Mouse CD1d (His & Fc Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 1 (CD1) is a member of CD system. It's a family of glycoproteins expressed on the surface of various human antigen- presenting cells which are implicated in the presentation of lipid antigens to T-cells. Due to the different lipid anchoring, the CD1 family is classified into two groups: group1 (CD1a-c) and group2 (CD1d). CD1d with lipid antigens activate NK T-cells which rapidly produce Th1 and Th2 cytokines after been activated.

Antigen-presenting glycoprotein CD1d1

CD1D1; CD1D; D POLYPEPTIDE; MGC34622; CD1.1; HMC CLASS I ANTIGEN-LIKE GLYCOPROTEIN CD1D; T-CELL SURFACE GLYCOPROTEIN CD1D; CD1D ANTIGEN; R3; CD1D MOLECULE; LY-38; THYMOCYTE ANTIGEN CD1D; ANTIGEN-PRESENTING GLYCOPROTEIN CD1D; DIFFERENTIATION ANTIGEN CD1-ALPHA-3; CD1A; R3G1; AI747460

P11609

Cd1d1; Cd1.1

Human Cells

A DNA sequence encoding the extracellular domain of mouse CD1D (NP_031665.2) (Met 1-Gly 305) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Mouse

The recombinant mouse CD1D /Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 532 amino acids and has a predicted molecular mass of 60.4 kDa.

> 80 % as determined by SDS-PAGE