Mouse Ccl8/Mcp2/Scya8 (His tag) recombinant protein

Mouse Ccl8/Mcp2/Scya8 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Chemokine ligand 8 (CCL8,MCP-2), is a small secreted cytokine which belongs to the intercrine beta (chemokine CC) family. CCL8 Chemotactic factor attracts monocytes. It can bind heparin.CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. Its ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.

chemokine (C-C motif) ligand 8(Ccl8)

Mcp2; Scya8

Q9Z121

Human Cells

A DNA sequence encoding the Mouse Ccl8/Mcp2/Scya8 Glu20-Pro97 is expressed

Mouse

>95% as determined by SDS-PAGE.