Mlpt peptide 3
Not For Human Use, Lab Use Only.
Cat.#: 300290
Special Price 189.8 USD
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Product Name
Mlpt peptide 3
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-MKLNGGKSLDPTGLY-OH
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Sequence
H-Met-Lys-Leu-Asn-Gly-Gly-Lys-Ser-Leu-Asp-Pro-Thr-Gly-Leu-Tyr-OH
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Length (aa)
15
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Peptide Purity (HPLC)
95.85%
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Molecular Formula
C70H116N18O22S
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Molecular Weight
1593.83
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Source
Synthetic
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Form
Powder
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Description
The source of Mlpt peptide 3 is red flour beetle (Tribolium castaneum). Mlpt (mille-pattes) is a new member of the gap family of segmentation genes in the flour beetle Tribolium. The mlpt gene have an unusual structure encoding a polycistronic mRNA that codes for four peptides. Mlpt peptide 3 is a one of them.
The expression of mlpt is not restricted to the blastoderm stage and the developing germband but occurs also at later stages and in various tissues, so it would seem possible that it has a role in multiple contexts. It also has a functional role in appendage formation. -
Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
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References
- Savard J, Marques-souza H, Aranda M, Tautz D. A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides. Cell. 2006;126(3):559-69.
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About TFA salt
Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.
TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.
TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.
In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
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• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"