MLF1 Polyclonal Antibody

Cat.#: 164245

Special Price 290.3 USD

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Product Information

  • Product Name
    MLF1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to MLF1
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    MLF1 antibody; myeloid leukemia factor 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic Peptide of human MLF1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
  • Validations

    Western blot - MLF1 Polyclonal Antibody

    Western blot - MLF1 Polyclonal Antibody

    Western blot analysis of extracts of mouse heart, using MLF1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"