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Product Name
MKNK2 antibody
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Description
MKNK2 Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive WB detected in mouse spleen tissue, MCF-7 cells. Observed molecular weight by Western-blot: 47 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GPRK7 antibody; MKNK2 antibody; MNK2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MKNK2 recombinant protein (Accession Number: BC018345). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IF: 1:10-1:100
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Validations
mouse spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:112667(MKNK2 Antibody) at dilution of 1:300
Immunofluorescent analysis of (-20oc Ethanol) fixed MCF-7 cells using Catalog No:112667(MKNK2 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
MKNK2(MAP kinase-interacting serine/threonine-protein kinase 2) is also named as GPRK7, MNK2 and belongs to the CAMK Ser/Thr protein kinase family.It has a conserved C-terminal Erk-interacting domain, a catalytic domain with homology to the calcium/calmodulin-dependent family of kinases, and putative MAP kinase phosphorylation sites located within the T loop of the kinase domain(PMID:9155017). The breast cancer cells express either an uncharacterized form of MNK2 or a cross-reacting MNK2-like protein with the band of 72-75 kDa by western blot(PMID:17130135).
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