Human MAD2L1/MAD2 (His Tag) recombinant protein
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Mitotic spindle assembly checkpoint protein MAD2A
Protein short names
HSMAD2; MAD2; MGC113763; AA673185; MAD2L1
A DNA sequence encoding the human MAD2L1 (Q13257) (Met 1-Asp 205) was expressed, with a polyhistide tag at the N-terminus.
The recombinant human MAD2L1 consisting of 221 amino acids and has a calculated molecular mass of 25.6 kDa. It migrates as an 28 kDa band in SDS-PAGE under reducing conditions as predicted.
> 96 % as determined by SDS-PAGE
Human MAD2L1 / MAD2 Protein (His Tag) SDS-PAGE
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