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Human MAD2L1/MAD2 (His Tag) recombinant protein

Cat.#: 501110

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Product Information

  • Product Name
    Human MAD2L1/MAD2 (His Tag) recombinant protein
  • Documents
  • Description
    Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
  • Protein name
    Mitotic spindle assembly checkpoint protein MAD2A
  • Protein short names
    HSMAD2; MAD2; MGC113763; AA673185; MAD2L1
  • Uniprot ID
    Q13257
  • Gene Name
    MAD2L1; MAD2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human MAD2L1 (Q13257) (Met 1-Asp 205) was expressed, with a polyhistide tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human MAD2L1 consisting of 221 amino acids and has a calculated molecular mass of 25.6 kDa. It migrates as an 28 kDa band in SDS-PAGE under reducing conditions as predicted.
  • Purity
    > 96 % as determined by SDS-PAGE
  • Validations

    Human MAD2L1 / MAD2 Protein (His Tag) SDS-PAGE

    Human MAD2L1 / MAD2 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"