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Human MICB (His Tag) recombinant protein

Cat.#: 501839

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Special Price 532.2 USD

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Product Information

  • Product Name
    Human MICB (His Tag) recombinant protein
  • Documents
  • Description
    Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
  • Protein name
    MHC class I polypeptide-related sequence B
  • Protein short names
    MICB; DAAP-210H10.1; PERB11.2
  • Uniprot ID
    X6R344
  • Gene Name
    MICB; PERB11.2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of human MICB (NP_005922.2) (Met 1-Gly 298) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human MICB consists of 287 amino acids and has a predicted molecular mass of 33 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh MICB is approximately 45-50 kDa due to glycosylation.
  • Purity
    > 98 % as determined by SDS-PAGE
  • Activity
    Immobilized human MICB-His (Cat:501839) at 10 μg/ml (100 μl/well) can bind S4-Fc3L3-NKG2D (Cat:501898), The EC50 of S4-Fc3L3-NKG2D (Cat:501898) is 0.52-1.2 μg/ml.
  • Validations

    Human MICB Protein (His Tag) SDS-PAGE

    Human MICB Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"