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Product Name
mGluR2 antibody
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Description
mGluR2 Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue. Positive WB detected in human brain tissue, HeLa cells, rat brain tissue. Observed molecular weight by Western-blot: 96 kDa,120 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GLUR2 antibody; GPRC1B antibody; GRM2 antibody; mGlu2 antibody; mGluR2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000839). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:500
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:112601(GRM2 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:112601(GRM2 Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:112601(GRM2 Antibody) at dilution of 1:200 (under 40x lens).
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Background
GRM2, also named as GPRC1B and MGLUR2, belongs to the G-protein coupled receptor 3 family. GRM2 is a receptor for glutamate. The activity of GRM2 is mediated by a G-protein that inhibits adenylate cyclase activity. It may mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
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References
- Javierre BM, Rodriguez-Ubreva J, Al-Shahrour F. Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells. Molecular cancer research : MCR. 9(8):1139-51. 2011.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"