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Product Name
MEN1 antibody
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Description
MEN1 Rabbit Polyclonal antibody. Positive IP detected in HepG2 cells. Positive WB detected in HepG2 cells, HeLa cells, Jurkat cells. Observed molecular weight by Western-blot: 63-70 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human; other species not tested.
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Alternative names
MEAI antibody; MEN1 antibody; Menin antibody; multiple endOCrine neoplasia I antibody; SCG2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MEN1 recombinant protein (Accession Number: NM_001370262). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:112653(MEN1 antibody) at dilution of 1:500
IP Result of anti-MEN1 (IP:Catalog No:112653, 4ug; Detection:Catalog No:112653 1:500) with HepG2 cells lysate 3200ug.
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Background
MEN1, also named as Menin or MEAI, is a tumor suppressor protein encoded by the MEN1 gene. Its inactivation has been implicated in tumors of many endocrine tissues. Germline inactivating mutations of MEN1 gene are the main cause of multiple endocrine neoplasia type 1 (MEN1), a syndrome characterized by tumors in the pituitary gland, the parathyroid glands, and the enteropancreatic neuroendocrine tissues.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"