-
Product Name
MED31 antibody
- Documents
-
Description
MED31 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, human brain tissue. Observed molecular weight by Western-blot: 16kd
-
Tested applications
ELISA, WB
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
3110004H13Rik antibody; CGI 125 antibody; FLJ27436 antibody; FLJ36714 antibody; hSOH1 antibody; MED31 antibody; mediator complex subunit 31 antibody; Mediator complex subunit SOH1 antibody; Soh1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of MED31 recombinant protein (Accession Number: NM_016060). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
-
Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:112591(MED31 antibody) at dilution of 1:600
-
Background
MED31, also named as SOH1 or CGI-125, is a 131 amino acid protein, which belongs to the Mediator complex subunit 31 family. MED31 localizes in the nucleus. MED31 as a component of the Mediator complex, a coactivator is involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED31 functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
-
References
- Risley MD, Clowes C, Yu M, Mitchell K, Hentges KE. The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development. Developmental biology. 342(2):146-56. 2010.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"