MED12L antibody

Cat.#: 112583

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Product Information

  • Product Name
    MED12L antibody
  • Documents
  • Description
    MED12L Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 260-280kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    MED12L antibody; TNRC11L antibody; FLJ46288 antibody; TRALP antibody; TRALPUSH antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_053002). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112583(MED12L antibody) at dilution of 1:500

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112583(MED12L antibody) at dilution of 1:500

  • Background
    MED12L, also named as KIAA1635, TNRC11L, TRALP and TRALPUSH, belongs to the Mediator complex subunit 12 family. MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED12L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED12L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The antibody can recognize all the isoform of MED12L. The antibody has no cross reaction to MED12.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"