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Product Name
MARVELD2 antibody
- Documents
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Description
MARVELD2 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, HEK-293 cells. Observed molecular weight by Western-blot: 64kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DFNB49 antibody; FLJ30532 antibody; MARVD2 antibody; MARVEL domain containing 2 antibody; MARVELD2 antibody; MRVLDC2 antibody; Tric antibody; Tricellulin antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MARVELD2 recombinant protein (Accession Number: XM_005248446). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:112483(MARVELD2 antibody) at dilution of 1:800
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Background
MARVELD2, also named as Tricellulin or TRIC, is a 558 amino acid protein, which contains one MARVEL domain. MARVELD2 localizes the cell membrane and plays a role in the formation of the epithelial barriers. MARVELD2, is a first integral membrane protein that is concentrated at the vertically oriented tight junction strands of tricellular contacts. MARVELD2 may be a component to maintain the integrity for peripheral nervous system myelin function and morphology.
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References
- Nayak G, Lee SI, Yousaf R. Tricellulin deficiency affects tight junction architecture and cochlear hair cells. The Journal of clinical investigation. 123(9):4036-49. 2013.
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