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MAPK11 antibody

Cat.#: 112431

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Product Information

  • Product Name
    MAPK11 antibody
  • Documents
  • Description
    MAPK11 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in human heart tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 42 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    MAP kinase 11 antibody; MAP kinase p38 beta antibody; MAPK 11 antibody; MAPK11 antibody; p38 2 antibody; P38B antibody; p38Beta antibody; P38BETA2 antibody; PRKM11 antibody; SAPK2 antibody; SAPK2B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of MAPK11 recombinant protein (Accession Number: NM_002751). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:112431(MAPK11 antibody) at dilution of 1:500

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:112431(MAPK11 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human brain using Catalog No:112431(MAPK11 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:112431(MAPK11 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:112431(MAPK11 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:112431(MAPK11 antibody) at dilution of 1:50 (under 10x lens)

  • Background
    MAPK11(Mitogen-activated protein kinase 11) is also named as PRKM11, SAPK2, SAPK2B,p38b and belongs to the MAP kinase subfamily.It is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors.In mouse brain, both p38a and p38b are present in neurons, while p38b is also expressed in glial cells(PMID:15748168).
  • References
    • Zheng S, Yang C, Liu T. Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"