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Product Name
MAP4K1 antibody
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Description
MAP4K1 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, Jurkat cells. Positive IP detected in Jurkat cells. Observed molecular weight by Western-blot: 90 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human; other species not tested.
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Alternative names
HPK1 antibody; MAP4K1 antibody; MEK kinase kinase 1 antibody; MEKKK 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MAP4K1 recombinant protein (Accession Number: NM_007181). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
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Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:112423(MAP4K1 antibody) at dilution of 1:1000
IP Result of anti-MAP4K1 (IP:Catalog No:112423, 4ug; Detection:Catalog No:112423 1:1000) with Jurkat cells lysate 3200ug.
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Background
MAP4K1(Mitogen-activated protein kinase kinase kinase kinase 1) is also named as MEKKK 1, HPK1 and belongs to the protein kinase superfamily. It may function as a novel tumor suppressor and its loss plays a critical role in pancreatic cancer. MAP4K1 regulates stress responses, proliferation, and apoptosis in hematopoietic cells. This protein has 2 isoforms produced by alternative splicing.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"