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MAOB antibody

Cat.#: 112470

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Product Information

  • Product Name
    MAOB antibody
  • Documents
  • Description
    MAOB Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue. Positive WB detected in human liver tissue, mouse liver tissue. Observed molecular weight by Western-blot: 59 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    MAO B antibody; MAOB antibody; Monoamine Oxidase B antibody; Monoamine oxidase type B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of MAOB recombinant protein (Accession Number: NM_000898). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112470(MAOB antibody) at dilution of 1:300

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112470(MAOB antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112470(MAOB antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112470(MAOB antibody) at dilution of 1:100 (under 10x lens)

  • Background
    The MAOB gene encodes a 520-amino acid protein with a molecular mass of 58.8 kD and shows 70% amino acid identity to MAOA. MAOA and MAOB are present in the outer mitochondrial membrane in the central nervous system and peripheral tissues.A comparison of highly purified human placental MAOA and human liver MAOB revealed that the A form of the enzyme is larger by 2 kDa and only one potential N-glycosylation site exists in each protein, with each site in a different relevant position (PMID:3387449).
  • References
    • Sai T, Uchida K, Nakayama H. Involvement of monoamine oxidase-B in the acute neurotoxicity of MPTP in embryonic and newborn mice. Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie. 65(4):365-73. 2013.
    • Sai T, Uchida K, Nakayama H. Changes of MAO-A and MAO-B Expressions in the Placenta of MPTP or MPP(+) Treated Mice. Journal of toxicologic pathology. 26(1):73-7. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"