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Product Name
Rat MBL-1 (Fc Tag) recombinant protein
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Description
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
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Protein name
Mannose-binding protein A
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Protein short names
GP58; MCFD1; ERGIC-53; MBP-A; MBL-A; FMFD1; S-MBP; F5F8D; MR60; MBL1; ERGIC53
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Uniprot ID
P19999
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Gene Name
Mbl1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat MBL1 (P19999) (Met1-Ala238) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat MBL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 462 amino acids and has a predicted molecular mass of 50.5 kDa. The apparent molecular mass of the protein is approximately 56 kDa in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Rat MBL1 Protein (Fc Tag) SDS-PAGE
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